Browsing by Author "Temel, Yusuf"
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Inhibitory effects of oxytocin and oxytocin receptor antagonist atosiban on the activities of carbonic anhydrase and acetylcholinesterase enzymes in the liver and kidney tissues of rats
Kocyigit, Umit M.; Taskiran, Ahmet Sevki; Taslimi, Parham; Yokus, Ahmet; Temel, Yusuf; Gulcin, Ilhami (WILEY, 2017)The aim of this study was to investigate the effects of oxytocin (OT), atosiban, which is an OT receptor antagonist, and OT-atosiban chemicals injected to rats on the activities of carbonic anhydrase (CA) and acetylcholinesterase ... -
Purification of glucose-6-phosphate dehydrogenase from <bold>rat</bold> (Rattus norvegicus) <bold>erythrocytes</bold> and inhibition effects of some metal ions on enzyme activity
Temel, Yusuf; Kocyigit, Umit M. (WILEY, 2017)Glucose-6-phosphate dehydrogenase (G6PD) is the first enzyme on which the pentose phosphate pathway was checked. In this study, purification of a G6PD enzyme was carried out by using rat erythrocytes with a specific activity ... -
Purification of glutathione S-transferase enzyme from quail liver tissue and inhibition effects of (3aR,4S,7R,7aS)-2-(4-((E)-3-(aryl)acryloyl)phenyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione derivatives on the enzyme activity
Temel, Yusuf; Kocyigit, Umit M.; Taysi, M. Serif; Gokalp, Faik; Gurdere, Meliha Burcu; Budak, Yakup; Ceylan, Mustafa; Gulcin, Ilhami; Ciftci, Mehmet (WILEY, 2018)The use of quail meat and eggs has made this animal important in recent years, with its low cost and high yields. Glutathione S-transferases (GST, E.C.2.5.1.18) are an important enzyme family, which play a critical role ... -
Synthesis and Carbonic Anhydrase Inhibition of Novel 2-(4-(Aryl)thiazole-2-yl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3(2H)-dione Derivatives
Kocyigit, Umit M.; Aslan, Osman Nuri; Gulcin, Ilhami; Temel, Yusuf; Ceylan, Mustafa (WILEY-V C H VERLAG GMBH, 2016)Carbonic anhydrase (CA, EC 4.2.1.1) is a member of the metalloenzyme family. It catalyzes the rapid conversion of carbon dioxide (CO2) and water to bicarbonate (HCO3-) and protons (H+) and also plays an important role in ... -
Synthesis, carbonic anhydrase I and II isoenzymes inhibition properties, and antibacterial activities of novel tetralone-based 1,4-benzothiazepine derivatives
Ceylan, Mustafa; Kocyigit, Umit M.; Usta, Necibe Canan; Gurbuzlu, Belma; Temel, Yusuf; Alwasel, Saleh H.; Gulcin, Ilhami (WILEY, 2017)Benzothiazepine compounds have a wide range of applications such as antibacterial, antidepressants, anticonvulsants, antihypertensives, antibiotics, antifungal, hypnotic, enzyme inhibitors, antitumor, anticancer and anti-HIV ...